Methylcobalamin (B12)

Methylcobalamin, plays a crucial role in various physiological functions. It is involved in the metabolism of every cell of the human body, especially affecting DNA synthesis and regulation, but also fatty acid synthesis and energy production. Methylcobalamin is also considered an essential vitamin for supporting brain health, nerve function, and the production of red blood cells.

Other Uses

Apart from its traditional uses, Methylcobalamin has other applications:

1. Neurological Health: Methylcobalamin is often used to treat vitamin B12 deficiency that leads to neurological complications. It's also used to treat conditions like peripheral neuropathy, diabetic neuropathy, and amyotrophic lateral sclerosis (ALS).

2. Sleep Disorders: Some research suggests that Methylcobalamin may affect melatonin secretion, enhancing the quality of sleep.

3. Homocysteine Level Regulation: Methylcobalamin, in combination with other B vitamins, can help regulate homocysteine levels, thus reducing the risk of heart disease.

Commonly Recommended Dosages

The recommended daily intake of vitamin B12 for adults is 2.4 micrograms. However, higher doses might be used therapeutically. For instance, to treat B12 deficiency, a typical dosage could be 1,000 micrograms of Methylcobalamin per day. High-dose supplementation should be done under the supervision of a healthcare provider.

Concentration and Route of Administration: Methylcobalamin is available in several forms, including tablets, sublingual tablets (dissolved under the tongue), lozenges, and injections. The concentration will depend on the specific product. For example, Methylcobalamin tablets commonly contain between 500 to 5000 micrograms per tablet.

Storage Conditions: Methylcobalamin should be stored in a cool, dry place away from direct sunlight. If it's a liquid formulation (like an injectable solution), it should be stored in the refrigerator. As always, keep it out of reach of children.

Please note: Always consult with a healthcare provider before starting any new supplement regimen. This information is based on current understanding as of the last update in September 2021 and might not reflect the latest research findings.